Table 2.
Demographic details of the populations studied: Lung transplant patients and previous acute rejection (ACR) episodes.
| Patient | Predisposing pathology | Time post transplant (months) | Grade ACR | Number of prior ACR episodes | Grade of prior ACR episodes | CsA/Tac levels* |
|---|---|---|---|---|---|---|
| 1 | Cystic Fibrosis | 6 | A0B0 | 1 | A2 | Tac 14·5 |
| 1 | 12 | A0B0 | 1 | A2 | Tac 11·4 | |
| 2 | Bronchiectasis | 6 | A0B0 | 0 | Tac 9 | |
| 3 | Pulmonary hypertension | 3 | A0BX | 0 | CsA 276 | |
| 3 | 9 | A0B0 | 0 | CsA 258 | ||
| 4 | Congenital bronchial webbs | 12 | A0BX | 2 | A3B0, A2B0 | CsA 300 |
| CsA 265 | ||||||
| 4 | 18 | A0B0 | 2 | A3B0, A2B0 | CsA 260 | |
| CsA 245 | ||||||
| 5 | Emphysema | 3 | A0B0 | 0 | Tac 6 | |
| 6 | Pulmonary hypertension | 6 | A0BX | 0 | CsA 349 | |
| 7 | Emphysema | 6 | A0B1 | 1 | A2B0 | CsA 152 |
| 7 | 9 | A0B0 | 1 | A2B0 | CsA 205 | |
| 8 | Pulmonary hypertension | 9 | A0BX | 0 | CsA 235 | |
| 8 | 9 | A0B0 | 0 | CsA 185 | ||
| 9 | Bronchiectasis | 9 | A0B0 | 0 | Tac 12 |
*
Therapeutic range for CsA (80–250 µg/l) and Tac (5–20 µg/l).