Table 1.
Day 14† | Day 35† | |
---|---|---|
Lung | ||
CNT | 5.10 ± 0.60 | 6.00 ± 0.52 |
DM | 5.65 ± 0.28§ | 7.52 ± 0.63§ |
DM/insulin | 5.28 ± 0.26¶ | 6.91 ± 0.39¶ |
Liver | ||
CNT | 6.46 ± 0.46 | 5.47 ± 0.56 |
DM | 7.16 ± 0.26§ | 6.39 ± 0.75§ |
DM/insulin | 6.43 ± 0.05** | 5.75 ± 0.27¶ |
Spleen | ||
CNT | 5.84 ± 0.45 | 4.88 ± 0.51 |
DM | 6.32 ± 0.24§ | 5.49 ± 0.69‡ |
DM/insulin | 6.06 ± 0.21¶ | 4.98 ± 0.22¶ |
Diabetic(DM) or Control (CNT) mice were infected with M. tuberculosis and DM mice received treatment with insulin. The number of live colonies in lung, liver and spleen on days 14 and 35 was measured.
Mean ± SD (CFU/organ) of 3 to 7 mice.
Not significant compared with CNT mice.
P < 0.05 compared with CNT mice.
Not significant compared with DM mice.
P < 0·05 compared with DM mice.