Fig. 2.

Representative photographs of adherence of CFDSE-labelled T lymphocytes in PCVs of Peyer's patches of AKR/J mice or SAMP1/Yit mice observed from the serosal side under an intravital microscope at 50–60 min after infusion of labelled T lymphocytes. (a) In AKR/J mice, there were a few adhered lymphocytes in PCVs of Peyer's patches. (b) On the other hand, in 35 week old SAMP1/Yit mice, there were a significant number of adhered lymphocytes. (c) Anti-MAdCAM-1 antibody significantly decreased the number of adhered T lymphocytes. (d) Anti-VCAM-1 antibody also decreased the number of adhered T lymphocytes (objective lens × 10).