Table 1.
Characteristics of the study group.
Patient | Sex | Age (years) | ESR (mm/h) | CRP (mg/l) | Medication | Disease activity | Organ involvement | cANCA titre |
---|---|---|---|---|---|---|---|---|
1 | Female | 21 | 10 | <5 | Prednisolone | Remission | ENT | Neg |
2 | Male | 33 | 18 | ″5 | Prednisolone | Remission | ENT | Neg |
3 | Female | 29 | 10 | <5 | Trim-Sulpha | Remission | ENT, lung | 1 : 32 |
4 | Male | 54 | 47 | 26 | CyclophosphamidePrednisolone | Active | kidney, ENT | 1 : 64 |
5 | Male | 65 | 11 | <5 | Prednisolone | Remission | ENT, kidney | 1 : 16 |
6 | Male | 59 | 17 | <5 | Trim-Sulpha | Remission | ENT, lung | Neg |
7 | Male | 60 | 34 | 11 | Prednisolone | Remission | ENT, kidney | 1 : 16 |
8 | Male | 23 | 61 | 29 | Cyclophosphamide Prednisolone | Active | ENT, kidney | 1 : 128 |
9 | Male | 36 | >100 | 161 | PrednisoloneTrim-Sulpha | Active | lung, kidney | 1 : 512 |
10 | Female | 78 | 21 | 13 | Prednisolone | Remission | ENT | Neg |
11 | Female | 35 | 10 | 14 | None | Remission | ENT, kidney | 1 : 16 |
12 | Female | 54 | 96 | 62 | CyclophosphamidePrednisolone | Active | ENT, kidney, lung | 1 : 512 |
13 | Female | 52 | ″8 | ″7 | None | Remission | ENT, lung | 1 : 16 |
14 | Female | 25 | 28 | 62 | CyclophosphamidePrednisolone | Active | Lung, kidney | 1 : 128 |
WG patients were classified as having active disease or being in remission based on clinical judgement¸ the Birmingham Vasculitis Activity Score as well as levels of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). Trim-Sulpha, trimethoprim-sulphametoxazol; ENT, ear, nose and throat; cANCA, cytoplasmic antineutrophil cytoplasmic antibodies. Organ involvement in those in remission represents previous involvement during active disease.