Fig. 7.

Corticosterone level in the serum from macrophage migration inhibitory factor (MIF) transgenic (Tg) mice and wild-type (WT) mice. The serum obtained before and 7 days after 1% dextran sulphate sodium (DSS) treatment was measured by enzyme-linked immunosorbent assay (ELISA). Corticosterone was significantly increased in WT mice treated with DSS compared with non-treated WT, non-treated MIF Tg and DSS-treated MIF Tg mice (*P < 0·05). The level of corticosterone in MIF Tg mice did not change between before and 7 days after DSS treatment. No significant differences were observed between non-treated WT, non-treated MIF Tg and DSS treated MIF Tg mice. All data are expressed as the mean ± s.e. There were five mice in each group. WT, WT mice; Tg, Tg mice.