Table 2.
MIF contents in the serum and colon in C57B6 and macrophage migration inhibitory factor (MIF) transgenic (Tg) mice.
| Serum (ng/ml) | Colon (ng/mg protein) | |
|---|---|---|
| WT + water | ″16·4 ± 1·6 | ″37·8 ± 2·7 |
| WT + DSS | ″25·0 ± 2·8* | ″63·0 ± 8·2* |
| MIF Tg + water | 229·8 ± 20·8** | 1152·0 ± 115·6** |
| MIF Tg + DSS | 2016·4 ± 349·4*** | 2053·6 ± 313·6*** |
Values are expressed as the mean ± s.e. n = 10 mice per group.
*
P < 0·05 versus the values in untreated WT mice;
**
P < 0·01;
***
P < 0·001 versus the values in wild-type (WT) mice treated with 1% dextran sulphate sodium (DSS) for 7 days.