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. 2005 Sep;141(3):509–517. doi: 10.1111/j.1365-2249.2005.02865.x

Fig. 1.

Fig. 1

Adhesion and MRP8/14 expression of monocytes in diabetes mellitus type 1 (DM1). (a) Monocytes of DM1 patients (n = 12) showed increased surface expression of MRP8/14 compared to healthy controls (n = 13) and DM2 patients (n = 3). The MRP8/14 expression is shown relative to that observed in healthy control subjects. The inlay shows representative histograms of monocytes of a DM1 patient and a healthy control; IgG controls and a DM2 patient are not shown to avoid overcrowding the figure. (b) The production of MRP8/14 by monocytes after 24 h was increased in DM1 patients (n = 9) in comparison to healthy controls (n = 9), both with and without fibronectin (FN) stimulation. (c) Monocytes of DM1 patients showed increased adhesion to FN in comparison to monocytes of healthy control subjects. Adhesion after 24 h is shown of nine DM1 patients and nine healthy control subjects. Data are presented as average ± s.e.m., *P < 0·05 as determined with unpaired two-tailed Students’t-test.