Fig. 4.

Outcome of proteinuria in rats treated with normal IgM and with IgM purified from serum of a patient with marked hyper IgM whose electrical charge was slightly more cationic than normal. Equal amounts (0.2 mg) of purified IgM were infused in the tail of 8 rats (4 normal and 4 cationic) at time 0 and every other days. Proteinuria was determined with the Coomassie dye binding assay and results are given as Mean ± standard deviation