Table 1. Clinical features of all nephrotic patients enrolled in the study that included (overall 48): (a) 8 pts with circulating auto-antibodies; (b) 5 pts with familial trait of nephritic syndrome; (c) 3 pts with NPHS1-NPHS2 mutations; (d) 32 pts with primary nephritic syndrome.

				Drug sensitivity FSGS/Mes
			Age at onset (years)			Histology
	n	Sex	mean (range)	Steroids	Cyclosporin	IgM	ESRF
Nephrotic syndrome with familial trait/NPHS1-2 mut	8	3F/5M	6·2 (2–8)	1S/2D/2R	2S/2R	2/2	2
Sporadic nephrotic syndrome	52	17F/35M	7·1 (1–36)	16S/21D/15R	23S/5R	28/9	11

FSGS, focal segmental glomerulosclerosis; Mes IgM, mesangial proliferation with deposits of IgM; ESRF, end stage renal failure; S, sensitive; D, dependent; R, resistant; NPHS1, gene encoding for nephrin; NPHS2, gene encoding for podocin.