Table 2. Frequency of infiltration into islets of Langerhans a.
| Marker | 5′ | 15′ | 30′ | 60′ | 120′ | 180′ | 240′ | 300′ | 360′ |
|---|---|---|---|---|---|---|---|---|---|
| TF | 2·6 ± 0·4b | 2·6 ± 0·4 | 2·4 ± 0·4 | 2·75 ± 0·2 | 2·6 ± 0·2 | 2·8 ± 0·2 | 3·0 ± 0·0 | 3·0 ± 0·0 | 3·0 ± 0·0 |
| CD16 | 0·25 ± 0·2 | 1·0 ± 0·4 | 1·2 ± 0·4 | 2·2 ± 0·5 | 2·6 ± 0·4 | 2·75 ± 0·2 | 2·75 ± 0·2 | 2·75 ± 0·2 | 3·0 ± 0·0 |
| Lysozyme | 1·0 ± 0·4 | 2·25 ± 0·2 | 2·25 ± 0·2 | 2·6 ± 0·2 | 2·6 ± 0·2 | 2·6 ± 0·4 | 2·6 ± 0·4 | 3·0 ± 0·0 | 2·8 ± 0·2 |
a
Staining for CD20, CD4, CD8, eosinophils (detected by cyanide-resistant endogenous peroxidase activity) and CD209 (DC-SIGN) were all negative, i.e. they were not detected in the islets.
b
Frequency of infiltration scored from 0 to 3, with 3 indicating strongly positive staining. All data are expressed as mean ± s.e.m.