Table 2.

Influence of dimethylfumarate (DMF) on the corneal inflammatory infiltration in the central cornea. Groups of mice were treated daily intraperitoneally with DMF or PBS 28 days before and 14 days after corneal HSV-1 infection. Immunohistochemical staining with antibodies directed against CD3, CD4 or CD8. Numbers of positively stained cells in a high-power field. Cell numbers were reduced in mice treated with DMF. Cell numbers, mean ± SEM.

	Groups
Antibodies	PBS	DMF	P-value
CD3	37·3 ± 7·5	6·8 ± 4·5	0·007
CD4	30·6 ± 4·2	6·8 ± 2·7	0·001
CD8	1·0 ± 0·5	0·8 ± 0·4	0·7