Table 4.

Cytokine production by HIV peptide-specific CD4⁺ T cells in chronic individuals.

Patient no.	Laboratory ID	CDC stage	Peptide no.	Region of protein	Amino acid sequence	Parental protein	CD69+ IL-2+ (%)	CD69+ IFN-γ+ (%)
1	111181	A1	13–14	Gag53–63	PGLLETSEGCK	p17	< 0·01	0·1
			62–63	Gag241–251	GTTSTLQEQIA	p24	< 0·01	0·12
2	111154	A2	5, 6	Gag25–35	RLRPGGKKHYM	p17	0·14	0·21
			59–60	Gag229–239	GQMREPRGSDI	p24	< 0·01	0·14
3	111221	A2	7, 8	Gag32–43	HYMLKHLVWAS	p17	< 0·01	0·23
			83–85	Gag324–338	LLVQNANPDCKTILR	p24	< 0·01	0·3
4	111246	A2	49–51	Gag188–201	NTMLNTVGGHQAAM	p24	< 0·01	0·3
5	111288	A2	43–44	Gag171–181	AFSPEVIPMFT	p24	0·38	0·14
6	111002	B2	64–66	Gag248–262	EQIAWMTSNPPVPVG	p24	< 0·01	0·12
			76–77	Gag296–306	FRDYVDRFFKT	p24	< 0·01	"0·11
7	111086	B2	1, 2	Gag5–15	ASILRGGKLDKW	p17	< 0·01	0·15
			21–22	Gag87–97	VATLYCVHAGI	p17	0·13	0·26
			45–46	Gag178–188	PMFTALSEGAT	p24	< 0·01	0·27
			54–55	Gag208–218	INEEAAEWDRL	p24	< 0·01	0·25
			56–57	Gag217–227	RLHPVHAGPIA	p24	< 0·01	0·3
			65–66	Gag251–261	WMTSNPPVPVG	p24	< 0·01	0·35
			100–101	Gag390–400	VKCFNCGKGEH	p15	< 0·01	0·36
			109–110	Gag426–436	DCTERQANFLG	p15	< 0·01	1·34
			120–121	Gag466–476	FEETTPAPPKQ	p15	0·08	0·25
			123–124	Gag479–489	KDREPLTSLKS	p15	< 0·01	0·2
8	110977	C3	62–63	Gag241–251	GTTSTLQEQIA	p24	< 0·01	0·12