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(a) Serum levels of total IgE (□, ▪) and specific IgE (○, •) were measured in the sensitized group (▪, •) and the saline group (□, ○) for 10 weeks. (b) Serum levels of specific IgG1 and IgG2a in both groups. Results are expressed as the mean of 5 mice ± SEM.