Table 2. Peptides from Schistosoma mansoni paramyosin selected by TEPITOPE algorithm.
| Peptide (amino acid position) | Amino acid sequence* | % HLA able to bind peptides according to TEPITOPE prediction | % individuals able to respond to peptide stimulation within the study population |
|---|---|---|---|
| Para (6–22) | TESHVKISRTIYRGVSP | 21 | 20 |
| Para (13–29) | SRTIYRGVSPSTTRLES | 13 | 11·6 |
| Para (151–167) | LDGALKAKQSAESKLEG | 8 | 16·5 |
| Para (168–184) | LDSQLNRLKSLTDDLQR | 17 | 12·6 |
| Para (210–226) | YEAQILNYSKAKSSLES | 21 | 18·5 |
| Para (355–371) | NSELIRRAKAAESLASD | 26 | 14·6 |
| Para (399–415) | RLKSLVNDLTDKNNLLE | 13 | 13·8 |
| Para (584–600) | AENNLQITEHKRLQLAN | 4 | 16 |
| Para (676–692) | NNEVLRLADELRQEQGN | 17 | 19·3 |
| Para (760–776) | FERQYKELQTQAEDDRR | 4 | 8·76 |
| Para (830–846) | AERTVTVRRVGPGGRAV | 13 | 16·5 |
*
Underlined amino acids correspond to the nonamer peptide predicted by TEPITOPE to bind different human leukocyte antigen (HLA)-DR.