Table 3. Human leucocyte antigen (HLA)-DR binding capacity of each paramyosin peptide selected by TEPITOPE.

		Binding capacity (IC 50 nM)
Sequence	Position	DR1 DRB1*0101	DR4w4 DRB1*0401	DR4w15 DRB1*0405	DR7 DRB1*0701	DR5w11 DRB1*1101	DR6w19 DRB1*1302	DR2w2 B1 DRB1*1501	DRw2B2 DRB5*0101	Molecules bound
TESHVKISRTIYRGVSP	6–22	870	3739	2399	288	198	457	387	28	6
SRTIYRGVSPSTTRLES	13–29	7·5	437	86	53	737	596	334	43	8
LDGALKAKQSAESKLEG	151–167	1406	6055	22267	21959	3039	23034	884	412	2
LDSQLNRLKSLTDDLQR	168–184	1280	34	14	8824	1985	9529	5599	314	3
YEAQILNYSKAKSSLES	210–226	49	861	12	10	23	255	42	28	8
NSELIRRAKAAESLASD	355–371	4·4	11	820	377	75	279	151	19	8
RLKSLVNDLTDKNNLLE	399–415	294	784	2630	–	–	84	–	–	3
AENNLQITEHKRLQLAN	584–600	1780	–	–	30	43	3721	59	18110	3
NNEVLRLADELRQEQGN	676–692	2804	7690	24506	–	4940	–	42159	1079	0
FERQYKELQTQAEDDRR	760–776	7·4	305	16	22380	89	–	5401	3098	4
AERTVTVRRVGPGGRAV	830–846	7·7	–	–	7855	9153	–	27	2·4	3

Significant affinity threshold < 1000, shown in bold type. Dash (–) means IC₅₀% > 30 000.