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. 2005 Dec;142(3):419–425. doi: 10.1111/j.1365-2249.2005.02944.x

Table 2. Classically activated Mφ generation in thermally injured mice treated with Ge-132.

Mφ from thermally injured SCIDbg mice treated with IL-10 IL-12 CCL3 CCL17
Saline 604 ± 130 < 20 < 18 527 ± 104
Ge-132 < 8* 616 ± 74* 2136 ± 277** < 16*

Thermally injured SCIDbg mice were treated with or without Ge-132 and infected with MRSA. Mφ from these mice 1 day after infection were cultured for 24 h. Culture fluids harvested 24 h after cultivation were assayed for cytokines and chemokines using ELISA. Data are expressed as mean (pg/ml) ± SD and representative of 3 experiments.

*

P < 0·01

**

P < 0·001 compared with thermally injured SCIDbg mice treated with saline.