Fig. 2.

Normal polyclonal immunoglobulins (IVIg) treatment increases macrophage/monocyte accumulation in the atherosclerotic lesions in the aortic root. (a) MOMA-2 staining of cross-sections of the aortic root from IVIg-treated and untreated third component-deficient (C3^−/−) apolipoprotein E (ApoE)^−/−low density lipoprotein receptor (LDLR)^−/− and C3^+/+ApoE^−/−LDLR^−/− mice. (b) MOMA-2 positive fraction area was measured on lesions on cryosections of the aortic root. Horizontal bars represent sample median. *P < 0·05.