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Proliferative response of B cell from young and aged mice Purified B cells from young (▪) and aged mice (□) were cultured with medium alone or F(ab)2 anti-µ for 24 and 48 h and the[3H] thymidine uptake (cpm) was measured. Results represent the mean + SD. The data are representative of three independent experiments. The asterisks indicate significant differences *P < 0·02 compared with stimulated-B cells from young animals.
