Skip to main content
. 2006 Feb;143(2):357–362. doi: 10.1111/j.1365-2249.2006.02997.x

Fig. 1.

Fig. 1

Blank column shows the proliferation of control lymphocytes (Ly) from MS patients and healthy controls (HC). When proliferation of MS patients’ Ly was measured upon coculture with autologous irradiated DC exposed to MBP (MBP-DC + Ly) or GA (GA-DC + Ly) or no antigen (DC + Ly), MBP-DC as well as control DC significantly enhanced autologous lymphocyte proliferation (shaded columns; P < 0·05 for both comparisons). This was not observed for GA-pulsed DC (black bar). In HC, coculture with DC resulted in elevated lymphocyte proliferation levels irrespective if the DC had been exposed or not to antigens (shaded columns; P < 0·05 for all 3 comparisons); *P < 0·05 for comparison between Ly and MLR. There is a significant difference in proliferation between autologous MLR with GA-DC pretreatment and MLR with MBP or without any DC pretreatment; #P < 0·05 for comparison between MLR with DC without pretreatment and MLR with GA-pretreatment. According to manufacturer (Amersham Biosciences), an OD of 1 corresponds to the proliferation of 500 cells/well of the tumoral cells L924 in 24 h.