Table 1.
Echocardiographic parameters 12 months after immunization with H26R.
| H26R immunized (n = 7) | Controls (n = 7) | P-value | |
|---|---|---|---|
| HR (beats/min) | 342 ± 10 | 366 ± 9 | n.s. |
| CO (ml/min) | 165 ± 2 | 164 ± 2 | n.s. |
| LVD (mm) | 9·0 ± 0·3 | 9·1 ± 0·2 | n.s. |
| LVS (mm) | 6·4 ± 0·2 | 5·7 ± 0·3 | 0·08 |
| Posterior wall thickness in end-diastole (mm) | 1·53 ± 0·13 | 1·50 ± 0·07 | n.s. |
| IVSd | 1·3 ± 0·3 | 1·3 ± 0·4 | n.s. |
| FS (%) | 31·2 ± 1·1 | 37·4 ± 2·5 | 0·02* |
| Circumferential shortening (circ/s) | 3·92 ± 0·16 | 5·17 ± 0·42 | 0·012* |
Data are given as mean ± s.e.m.. Differences between groups were calculated with the Mann–Whitney test, * P < 0·05. HR = heart rate; CO = cardiac output (stroke volume · heart rate); LVD = left ventricle end-diastolic diameter; LVS = left ventricle end-systolic diameter; PWd = posterior wall diameter; IVSd = intraventricular septum thickness in end diastole; FS = fractional shortening (LVD-LVS/LVD × 100); circumferential fibre shortening (fraction shortening/ejection time).