Table 1.
Percentages of CD69+ cells within T-cell subsets in allo-, auto- and PHA-stimulated PBMC cultures after 40 h of incubation.
| percentage CD69, median (interquartile range) | ||||
|---|---|---|---|---|
| T-cell subset | FBDs (n = 18) | ESN FSWs (n = 20) | P-value* | P-value† |
| Allostimulation | ||||
| CD4+ | 29·8 (18·9–39·5) | 23·4 (14·6–32·8) | 0·219 | 0·095 |
| CD4+ CD45RO– | 27·2 (18·0–35·4) | 22·3 (13·6–35·0) | 0·447 | 0·238 |
| CD4+ CD45RO+ | 32·2 (19·2–45·2) | 25·5 (15·0–33·3) | 0·136 | 0·030 |
| CD8+ | 25·0 (17·5–35·8) | 23·7 (16·4–29·9) | 0·388 | 0·050 |
| CD8+ CD45RO– | 24·6 (16·3–34·8) | 24·0 (16·3–29·8) | 0·640 | 0·104 |
| CD8+ CD45RO+ | 27·8 (23·3–40·5) | 21·8 (17·0–27·5) | 0·035 | 0·006 |
| Autostimulation | ||||
| CD4+ | 32·0 (11·5–42·5) | 24·9 (15·8–30·4) | 0·279 | 0·064 |
| CD4+ CD45RO– | 29·7 (10·9–40·5) | 22·0 (15·1–32·4) | 0·397 | 0·091 |
| CD4+ CD45RO+ | 32·9 (12·0–45·0) | 23·1 (17·0–33·1) | 0·267 | 0·044 |
| CD8+ | 24·1 (10·8–36·2) | 19·8 (15·6–24·5) | 0·397 | 0·032 |
| CD8+ CD45RO– | 22·2 (8·0–33·9) | 18·8 (12·4–23·7) | 0·520 | 0·062 |
| CD8+ CD45RO+ | 35·0 (21·3–42·1) | 24·9 (18·9–30·3) | 0·050 | 0·007 |
| PHA-stimulation | ||||
| CD4+ | 97·6 (96·9–98·4) | 98·1 (97·1–98·6) | 0·349 | 0·770 |
| CD4+ CD45RO– | 97·8 (96·2–98·7) | 98·4 (97·0–98·8) | 0·405 | 0·851 |
| CD4+ CD45RO+ | 98·0 (96·6–98·4) | 97·8 (96·8–98·5) | 0·907 | 0·923 |
| CD8+ | 91·1 (87·4–93·5) | 94·1 (93·1–96·4) | 0·019 | 0·167 |
| CD8+ CD45RO– | 90·3 (84·7–93·1) | 94·0 (91·5–96·1) | 0·018 | 0·128 |
| CD8+ CD45RO+ | 94·2 (91·3–95·7) | 95·3 (91·9–96·7) | 0·373 | 0·916 |
*
Mann–Whitney u-test.
†
Linear regression adjusting for age; all variables are normally distributed. P-values < 0·05 are in bold.