Table 4.

Predisposing factors for osteomyelitis (OM) in the patients, carriers of the different TLR4 Asp(299)Gly genotypes.

Predisposing factors	TLR4 GG (n = 3)	TLR4 AG (n = 12)	TLR4 GG + AG (n = 15)	TLR4 AA (n = 65)	P-value
Paraplegia (%)	0/3 (0)	2/12 (16·7)	2/15 (13·3)	10/65 (15·4)	NS
Peripheral vascular disease (%)	0/3 (0)	1/12 (8·3)	1/15 (6·7)	5/65 (7·7)	NS
Cavus foot (%)	1/3 (33·3)	1/12 (8·3)	2/15 (13·3)	2/65 (3·1)	NS
Other factors (%)*	0/3 (0)	1/12 (8·3)	1/15 (6·7)	5/65 (7·7)	NS
Diabetes	0/3 (0)	1/12 (8·3)	1/15 (6·7)	9/65 (13·8)	NS
Total factors (%)	1/3 (33·3)	6/12 (50·0)	7/15 (46·7)	31/65 (47·7)	NS

NS, not significant.

^*osteopetrosis, sensitive polineuropathy, hip dysplasia, Ewing sarcoma, prostate cancer, Munchausen syndrome.