Table 4.
Predisposing factors for osteomyelitis (OM) in the patients, carriers of the different TLR4 Asp(299)Gly genotypes.
| Predisposing factors | TLR4 GG (n = 3) | TLR4 AG (n = 12) | TLR4 GG + AG (n = 15) | TLR4 AA (n = 65) | P-value |
|---|---|---|---|---|---|
| Paraplegia (%) | 0/3 (0) | 2/12 (16·7) | 2/15 (13·3) | 10/65 (15·4) | NS |
| Peripheral vascular disease (%) | 0/3 (0) | 1/12 (8·3) | 1/15 (6·7) | 5/65 (7·7) | NS |
| Cavus foot (%) | 1/3 (33·3) | 1/12 (8·3) | 2/15 (13·3) | 2/65 (3·1) | NS |
| Other factors (%)* | 0/3 (0) | 1/12 (8·3) | 1/15 (6·7) | 5/65 (7·7) | NS |
| Diabetes | 0/3 (0) | 1/12 (8·3) | 1/15 (6·7) | 9/65 (13·8) | NS |
| Total factors (%) | 1/3 (33·3) | 6/12 (50·0) | 7/15 (46·7) | 31/65 (47·7) | NS |
NS, not significant.
*
osteopetrosis, sensitive polineuropathy, hip dysplasia, Ewing sarcoma, prostate cancer, Munchausen syndrome.