Fig. 2.

Quantification of leucocyte recruitment in the choroid plexus of MRL^+/+ and MRL/MpJ-fas^lpr mice at 16 and 20 weeks. Brains were sectioned at regular intervals and leucocyte recruitment identified using immunohistochemistry for CD45. (a,c) Area of the choroid plexus in MRL^+/+ and MRL/MpJ-fas^lpr mice at 16 (a)and 20 (c)weeks. (b,d) Density of CD45⁺ leucocyte infiltrate present in the choroid plexus of both mouse strains at 16 (b) and 20 (d)weeks. n = 6–8 mice per group. Data are shown as mean ± s.e.m. *P < 0·05 versus MRL^+/+ mice.