. 2006 May;144(2):299–308. doi: 10.1111/j.1365-2249.2006.03056.x

Table 1.

Circulating leucocyte counts and leucocyte subsets in MRL^+/+, MRL/MpJ-fas^lpr, P-selectin^–/– -MRL/MpJ-fas^lpr, and intercellular adhesion molecule-1 (ICAM-1)^–/– -MRL/MpJ-fas^lpr mice at 8, 16 and 20–25 weeks of age.^*

		M1/70^hi/Gr-1^hi	M1/70 ^hi/Gr-1^int	CD3⁺	B220⁺/CD3^–
	Total	(PMNs)	(monocyte lineage)	(T cells)	(B cells)
MRL^+/+
8 weeks	6·8 ± 0·5 (6)	1·5 ± 0·1 (6)	0·20 ± 0·28 (6)	3·2 ± 0·3 (6)	2·1 ± 0·2 (6)
16 weeks	7·4 ± 0·5 (6)	1·6 ± 0·1 (6)	0·20 ± 0·01 (6)	3·2 ± 0·2 (6)	1·7 ± 0·1 (6)
20–25 weeks	4·9 ± 0·6 (7)	1·3 ± 0·2 (7)	0·14 ± 0·05 (7)	1·9 ± 0·2 (7)	0·9 ± 0·2 (7)
MRL/MpJ-fas^lpr
8 weeks	5·3 ± 0·4 (6)	0·9 ± 0·1 (6)^†	0·07 ± 0·01 (6)^†	2·0 ± 0·1 (9)^†	1·0 ± 0·1 (9)^†
16 weeks	19·4 ± 3·8 (6)	4·5 ± 0·9 (6)^†	0·77 ± 0·17 (6)^†	12·8 ± 1·3 (6)^†	1·4 ± 0·1 (6)
20–25 weeks	29·6 ± 4·1 (7)	5·3 ± 1·8 (6)^†	0·72 ± 0·18 (6)^†	20·8 ± 1·6 (6)^†	2·0 ± 0·2 (6)^†
P-selectin^–/–-MRL/MpJ-fas^lpr
8 weeks	10·9 ± 0·5 (9)	4·4 ± 0·3 (8)^**	0·56 ± 0·07 (8)^**	3·1 ± 0·4 (6)^**	1·7 ± 0·3 (6)^**
16 weeks	20·2 ± 4·9 (5)	5·7 ± 0·7 (6)	0·79 ± 0·14 (6)	10·7 ± 0·8 (8)	2·8 ± 0·2 (8)^**
20–25 weeks	27·8 ± 4·9 (6)	6·5 ± 1·6 (6)	0·72 ± 0·16 (6)	14·6 ± 1·6 (7)^**	3·1 ± 0·4 (7)^**
ICAM-1^–/–-MRL/MpJ-fas^lpr
16 weeks	16·1 ± 4·4 (5)	3·2 ± 0·8 (6)	0·50 ± 0·13 (6)	7·3 ± 0·7 (8)^**	2·0 ± 0·2 (8)^**
20–25 weeks	28·7 ± 6·7 (5)	4·3 ± 0·8 (6)	0·51 ± 0·09 (6)	18·1 ± 0·8 (6)	4·7 ± 0·7 (6)^**

Data are expressed as cells × 10⁶/ml ± s.e.m. The number of mice sampled is shown in parentheses.

^†

P < 0·05 versus MRL^+/+ at same age.

^**

P < 0·05 versus MRL/MpJ-fas^lpr at same age.