. 2006 May;144(2):299–308. doi: 10.1111/j.1365-2249.2006.03056.x

Table 2.

Phenotypes of circulating CD3⁺ leucocytes in MRL^+/+, MRL/MpJ-fas^lpr, P-selectin^–/– MRL/MpJ-fas^lpr and intercellular adhesion molecule-1 (ICAM-1)^–/– MRL/MpJ-fas^lpr mice at 8, 16 and 20–25 weeks of age.^*

	CD4⁺	CD8⁺	CD4^–/CD8^– (DN)	B220⁺
MRL^+/+
8 weeks (6)	1·75 ± 0·05 (6)	1·30 ± 0·03 (6)	0·09 ± 0·02 (6)	0·98 ± 0·43 (6)
16 weeks (7)	1·50 ± 0·10 (7)	1·40 ± 0·10 (7)	0·22 ± 0·08 (7)	0·35 ± 0·11 (6)
20–25 weeks (7)	1·04 ± 0·04 (7)	0·82 ± 0·05 (7)	0·06 ± 0·02 (7)	0·05 ± 0·01 (7)
MRL/MpJ-fas^lpr
8 weeks (9)	0·86 ± 0·04 (9)^†	0·91 ± 0·03 (9)^†	0·18 ± 0·01 (9)^†	0·38 ± 0·03 (9)
16 weeks (6)	1·75 ± 0·17 (6)	2·50 ± 0·39 (6)^†	8·46 ± 0·55 (6)^†	9·20 ± 1·32 (6)^†
20–25 weeks (6)	2·71 ± 0·18 (6)^†c	3·56 ± 0·24 (6)^†	14·42 ± 0·34 (6)^†	14·33 ± 0·67 (6)^†
P-selectin^–/–-MRL/MpJ-fas^lpr
8 weeks (8)	1·44 ± 0·03 (8)^**	1·44 ± 0·03 (8)^**	0·24 ± 0·02 (8)^**	0·54 ± 0·09 (6)^**
16 weeks (6)	1·69 ± 0·23 (6)	1·52 ± 0·29 (6)^**	7·43 ± 0·41 (6)	7·50 ± 0·93 (8)
20–25 weeks (7)	2·35 ± 0·18 (7)	2·06 ± 0·44 (7)^**	10·17 ± 0·43 (7)^**	10·76 ± 1·36 (7)^**
ICAM-1^–/–-MRL/MpJ-fas^lpr
16 weeks (6)	1·43 ± 0·11 (6)	1·50 ± 0·19 (6)^**	4·29 ± 0·30 (6)^**	3·30 ± 0·77 (8)^**
20–25 weeks (6)	4·14 ± 0·23 (6)^**	3·41 ± 0·12 (6)	10·49 ± 0·30 (6)^**	11·73 ± 0·77 (6)^**

CD4⁺, CD8⁺, CD4^–/CD8^– and B220⁺data are expressed as cells × 10⁶/ml ± s.e.m. based on the total CD3⁺ cell count, and percentage data for each subclass. The number of mice sampled is shown in parentheses.

^†

P < 0·05 versus MRL^+/+ at same age.

^**

P < 0·05 versus MRL/MpJ-fas^lpr at same age.