Fig. 2.

Clinical signs of experimental autoimmune myasthenia gravis (EAMG) and effects of surgical denervation. Clinical score changes in non-denervated (solid squares); denervated (open circles) and sham-operated (open triangles) female Lewis rats after immunization with acetylcholine receptor (AChR) + complete Freund's adjuvant (CFA). The clinical severity of EAMG was graded blindly as described in the Materials and methods section. Symbols refer to mean values, and bars to standard deviation. Denervated immunized rats had less clinical severity scores at all points when compared with non-denervated immunized controls (**P< 0·001). There was no statistical difference between sham-operated immunized rats and non-denervated immunized controls.