Fig 1.

Representative dot plots showing interferon (IFN)-γ production by CD8⁺ and CD8⁻ (CD4⁺) T cells from blood, bronchoalveolar lavage (BAL) and bronchial brushing (BB) in a lung transplant patient. T cells were identified by CD3 PC5 versus side scatter characteristics. Transplant patients showed an increase in the percentage of CD8⁺ T cells producing IFN-γ in BB compared with blood. Transplant patients showed an increase in IFN-γ in both CD4⁺ and CD8 T cells in BB compared with BAL. Note the decrease CD4⁺ and increase in CD8⁺ T cells in BB compared with blood and BAL.