Table 2.

Lung transplant patients and previous acute cellular rejection (ACR) episodes.

Patient	Predisposing pathology	Time post-transplant at FOB†	Grade ACR‡	No. prior ACR episodes	Grade prior ACR episodes	Time post-transplant (current)	CsA/Tac levels*
1	Cystic fibrosis	6 m	A0B0	1	A2Bx	20 m	Tac 14·5
1	Cystic fibrosis	12 m	A0B0	1	A2Bx
2	Bronchiectasis	6 m	A0B0	0		6 m	Tac 9
3	Pulmonary hypertension	3 m	A0BX	0		19 m	CsA 276
3		9 m	A0B0	0			CsA 216
4	Congenital bronchial webbs	12 m	A0BX	2	A3B0, A2B0	30 m	CsA 185
4	Congenital bronchial webbs	18 m	A0B0	2	A3B0, A2B0		CsA 235
5	Emphysema	3 m	A0B0	0		18 m	CsA 195
6	Pulmonary hypertension	6 m	A0BX	0		19 m	CsA 276
7	Emphysema	6 m	A0B1	1	A2B0	13 m	CsA 152
7		10 m	A0B0	1	A2B0		CsA 180
8	Pulmonary fibrosis	9 m	A0BX	0		12 m	Tac 15
8		6 m	A0B1	1			Tac 12
9	Cystic fibrosis	9 m	A0B0	0		18 m	CsA 120

^*Therapeutic range for cyclosporin A (CsA) (80–250 µg/l) and tacrolimus (Tac) (5–20 µg/l).

^†Time in months post-transplant at fibreoptic bronchoscopy.

^‡Acute rejection grade.