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Clinical and functional data of the subjects included in the study.
| Never smokers (n = 7) | Smokers with normal lung function (n = 16) | COPD patients (n = 14) | |
|---|---|---|---|
| Age (years) | 57 ± 5 | 61 ± 2 | 64 ± 2 |
| Smoking history (pack- years) | 0 | 38 ± 4 | 45 ± 4 |
| FEV1 (% ref) | 97 ± 6 | 93 ± 3 | 57 ± 2† |
| FEV1/FVC (%) | 77 ± 2 | 74 ± 1 | 55 ± 2† |
P < 0·01 [chronic obstructive pulmonary disease (COPD) versus with normal lung function and never smokers]. FEV1 = forced expiratory volume in 1 s.
