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Immunogold labeling of COL8A2 in the rough endoplasmic reticulum (ER) of the endothelial cell in case 1 of early-onset FCD. Abundant rough ER in the endothelial cell showed many gold-labeling particles on the ER membrane structures (arrows). A, low magnification; B, high magnification; C, negative control in a similar area of adjacent section.
