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. 2007 Feb 8;3:5. doi: 10.1186/1860-5397-3-5

Table 1.

Condensation of substituted benzaldehydes with 5.

benzaldehyde substituent product diastereomeric ratio (cis/trans)a yield (DCM)b yield (CHCl3)c

H 7a 1 : 3 49 56
2-OMe 7b 1 : 1 51 58
3-OMe 7c 1 : 3 30 36
4-OMe 7d 1 : 5 48 60
2-OPiv 7e 1 : 3 48 62
3-OPiv 7f 1 : 5 42 44
4-OPiv 7g 1 : 3 47 58

a: As deduced by analysis of 1H NMR spectra or after CC separation b: reflux; c: 20°C.