Table 2.
Association of RNAP IV-dependent and independent siRNAs with AGO1 and AGO4
| siRNA | Total (%)* | RNAP IV independent (%)† |
|---|---|---|
| Total | ||
| Wild type | 35,473 | 3,438 (9.7) |
| AGO1 | 8,544 | 3,791 (44.4) |
| AGO4 | 13,738 | 1,102 (8.0) |
| 21 mers | ||
| Wild type | 3,609 (10.2) | 1,427 (39.5) |
| AGO1 | 6,046 (70.8) | 3,048 (50.4) |
| AGO4 | 473 (3.4) | 64 (13.5) |
| 22 mers | ||
| Wild type | 4,459 (12.6) | 984 (22.1) |
| AGO1 | 2,472 (28.9) | 742 (30.0) |
| AGO4 | 1,843 (13.4) | 185 (10.0) |
| 24 mers | ||
| Wild type | 27,405 (77.3) | 1,027 (3.7) |
| AGO1 | 26 (0.3) | 1 (3.8) |
| AGO4 | 11,422 (83.1) | 853 (7.5) |
*The total of individual 21-, 22-, and 24-mer siRNAs. Numbers in parentheses show the percentage of siRNAs that belonged to the corresponding size class.
†Derived from siRNA clusters in nrpd1a/1b. Numbers in parentheses show the percentage of total siRNAs that are RNAP IV-independent.