Figure 3.
Multiple 100 Hz TENS treatments given once-a-week reduce joint swelling and pain scores in the stable period of rat monoarthritis induced by intra-articular injection of CFA at the right ankle. TENS treatments with medium intensity (1-2-3 mA) were administered from fourth week through ninth week after the injection of CFA (shown by arrows on the horizontal bar). *P < 0.05, **P < 0.01 compared with control group at the same time point [ANOVA followed by Duncan's test for the body weight and ankle circumferences in (A) and (B), Kruskal–Wallis ANOVA followed by Dunn's test for the pain scores in (C) and (D)]. #P < 0.05 compared between two groups from fifth week through ninth week (two-way ANOVA).