Table 3.

Icv administration of L-NAME, ODQ and KT5823 reduced proceptivity induced by VCS in ovx rats primed with 5 μg of E₂B

		0 min		120 min
		% Proceptve Females		% Proceptve Females
	N	15 minutes	60 minutes	15 minutes	60 minutes
Vehicle	21	33		67
L-NAME 500 μg	8	12	0	12+	0+
ODQ 22 μg	8	12	0	0**	0+
KT5823 0.12 μg	8	0		0**

Proceptive behavior in ovx female rats primed with 5 μg of E₂B was tested 0 and 120 min after application of VCS. Drugs or vehicle were infused into the right lateral ventricle 15 min before VCS as in Fig. 2A. Vehicle data are combined from the rows labeled “saline” and “DMSO” in Table 1. Other females were injected with L-NAME or ODQ 60 min before application of VCS (see Fig. 2B for lordosis data).

⁺P<0.05;

^**P<0.001 vs. corresponding vehicle.