Table 1.

SAD risk according to age, sex, vaccination and infectious disease history.

Characteristic	SAD percentage (n)	RR (95% CI)	P-value
Males	15·6 (7/45)	1·13 (0·36–3·52)	0·26
Females	13·8 (4/29)	1·0
Age under 5 years	15·8 (6/38)	1·14 (0·38–3·40)	0·25
Age 5 years or over	13·9 (5/36)	1·0
Previous pneumococcal vaccine	11·1 (1/9)	0·82 (0·12–5·80)	0·41
No previous pneumococcal vaccine	13·6 (8/59)	1·0
History of otitis media	18·9 (7/37)	4·73 (0·62–36·12)	0·08
No history of otitis media	4·0 (1/25)	1·0
≥ Eight episodes of otitis media per year	20·0 (3/15)	2·30 (0·58–9·13)	0·17
< Eight episodes of otitis media per year	8·7 (4/46)	1·0
Spontaneous tympanic membrane perforation	7·1 (1/14)	0·48 (0·06–3·57)	0·30
No spontaneous tympanic membrane perforation	14·9 (7/47)	1·0
Chronic otorrhoea	36·4 (4/11)	4·64 (1·36–15·75)	0·02*
No chronic otorrhoea	7·8 (4/51)	1·0
Recurrent bronchitis or pneumonia	15·6 (5/32)	1·56 (0·41–5·98)	0·24
No recurrent bronchitis or pneumonia	10·0 (3/30)	1·0
Other significant infection	13·3 (2/15)	1·04 (0·24–4·64)	0·33
No other significant infection	12·8 (6/47)	1·0

^*P < 0·05 Fisher’s exact test.