Table 1.

Examples of Neuropathic Pain Conditions

Disease	Pathology	Symptoms	Hyperalgesia			Special Features
			Cooling	Heat	Mechanical
Traumatic neuropathy	Axotomy distal to DRG	Ongoing pain	++	+	++	Great variety of presentations
Tic douloureux	Compression (often vascular) of trigeminal nerve near brainstem	Lightening-like attacks of pain	?	?	+++	Mechanical stimuli evoke attacks of pain
Painful diabetic neuropathy	Length-dependent neuropathy	Burning pain in the feet	−	+	+/−	Neuropathy sometimes affects small fibers exclusively
Postherpetic neuralgia	Results from damage by herpes zoster infection of peripheral nerve	Burning pain	+/−	+/−	++	Pain follows the distribution of the affected dermatomes