Fig. 4.

Effect of resveratrol (RVT) and curcumin (CMN) on IgG1 and IgG2a production by lymphocytes. RVT and CMN were cultured in different concentrations (1, 5, 10 and 20 μM) with lipopolysaccharide (LPS) (5 μg/ml)-stimulated lymphocytes. The supernatants were collected after 48 h and isotypes were measured by enzyme-linked immunosorbent assay (ELISA). All the data were calculated as pg/ml of IgG1 (a) and IgG2a (b) computed by comparison with the standard curve using standard IgG1 and IgG2a isotypes. Data expressed are the mean ± standard error (s.e.) from triplicate samples. *P < 0·05 compared to the release in LPS treated cells.