Table 2.
Absolute numbers of basic lymphocyte subpopulations in IgAD, CVID and controls. Results are expressed as median ± standard deviation (s.d.)
| Controls (n = 65) | IgAD (n = 85) | CVID (n = 47) | P, IgAD controls | P, IgAD CVID | |
|---|---|---|---|---|---|
| Leucocytes (109/l) | 6±1 ± 1±5 | 6±1 ± 1±6 | 6±3 ± 2±3 | 0·962 | 0·483 |
| Lymphocytes (109/l) | 1±89 ± 0±12 | 1±77 ± 0±12 | 1±61 ± 0±25 | 0·170 | 0·186 |
| CD3+ (109/l) | 1±32 ± 0±49 | 1±25 ± 0±43 | 1±22 ± 0±77 | 0·231 | 0·483 |
| CD4+ (109/l) | 0±89 ± 0±36 | 0±75 ± 0±28 | 0±54 ± 0±32 | 0·006* | < 0·001* |
| CD8+ (109/l) | 0±39 ± 0±32 | 0±43 ± 0±20 | 0±58 ± 0±50 | 0·143 | 0·023 |
| CD19+ (109/l) | 0±21 ± 0±09 | 0±20 ± 0±11 | 0±15 ± 0±18 | 0·905 | 0·023 |
| CD16/56+ CD3– (109/l) | 0±24 ± 9±20 | 0±22 ± 0±13 | 0±14 ± 0±11 | 0·117 | 0·003* |
*
Indicates statistically significant difference using critical value after Bonferroni's correction: 0±007. CVID: common variable immunodeficiency; IgAD: selective deficiency of immunoglobulin A.