Fig. 1.

Sulfatase activities in Sumf1^−/− MEFs. ARSA (a), ARSB (b), ARSC (c), ARSE (d), SGSH (e), iduronate-2-sulfatase (IDS) (f), G6S (g), GAL6S (h), and B-Gal (i) activities were measured in MEFs derived from two separate Sumf1^−/− mice (KO1 and KO2) and WT littermates. Sulfatase activities are undetectable in the Sumf1^−/− MEFs and are partially rescued when the cells are transduced by a lentiviral vector containing the human SUMF1 cDNA (KO+SUMF1). WT indicates average values and standard deviations of four WT mice. KO+SUMF1 indicate average values and standard deviations of two Sumf1^−/− MEF lines from two different mice, each transduced in duplicate. All enzymatic activities are indicated as nmol/h/mg.