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. Author manuscript; available in PMC: 2007 Mar 6.
Published in final edited form as: Structure. 2007 Jan;15(1):7–19. doi: 10.1016/j.str.2006.11.008

Figure 6.

Figure 6

SSEhunter skeleton from segmented cryoEM density of RDV P8. The segmented cryoEM density is shown in grey with the skeleton in red (A). In (B), a zoomed in view of portion of the lower domain of P8 is shown with the X-ray structure (1UF2, ribbon) superimposed on the density map and skeleton, illustrating the ability of the skeleton to approximate the polypeptide chain. While the skeleton does approximate the overall path of the polypeptide chain, the exact path in the skeleton is ambiguous in certain regions containing branches and breaks corresponding to the density features.