Figure 6.

The NterC region requires additional HD and/or C-terminal sequences to confer AbdA mesodermal activity. The effect of endogenous expression of the C1 fusion product (the structure of the protein is shown, Top) on wg and dpp expression in the VM was analyzed. (A) wg is not expressed in homozygous UbxC1. (B and C) Most Homozygous Ubx^C1 embryos show a severe reduction or absence of dpp expression in the central midgut VM, whereas expression in the anterior midgut is not altered (B). A minority exhibits some posterior ectopic expression in the expression domain of the C1 fusion protein. (C and D) Providing high level of Dpp signaling with a heat-inducible transgene (HS.dpp) to homozygous Ubx^C1 embryos does not restore wg expression.