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. 2007 Mar 9;3(3):e26. doi: 10.1371/journal.ppat.0030026

Figure 3. The Toll Pathway Is Required for the Primed Response.

Figure 3

Partial loss-of-function alleles of PGRP-SA (circles) and imd (triangles) were injected with PBS (open shapes) or dead S. pneumoniae (filled shapes) on day 0 and challenged 1 wk later with a lethal dose of S. pneumoniae (20 CFU for PGRP-SAseml and 100 CFU for imd10191). Log-rank analysis of the survival curves indicates that naïve and S. pneumoniae–primed PGRP-SAseml flies die at the same rate, whereas the curves for naïve and S. pneumoniae–primed imd10191 flies are significantly different (p < 0.0001). n = 154 to 245 for each condition. Molecular information for imd10191 is given in Materials and Methods.