Figure 4. Forearm blood flow responses to administration of isoprenaline via the brachial artery in Gly16 and Arg16 subjects following dietary sodium restriction.

Baseline FBF did not differ between groups. Isoprenaline caused an increase in FBF that was not different in the two genotype groups (P = 0.51, main effect of genotype; P = 0.72, genotype-by-isoprenaline interaction). NOS inhibition with l-NMMA (lower panel) decreased baseline FBF, and significantly blunted the response to isoprenaline, but there was no evidence to suggest the responses were influenced by genotype (P = 0.89, genotype-by-isoprenaline-by-l-NMMA interaction).