Table 2.
Weight loss and urinary indices before and after dietary sodium restriction
| Na+ intake | Arg16 | Gly16 | Pdiet | Pgenotype | Pinteraction |
|---|---|---|---|---|---|
| Weight (kg) | |||||
| NL | 70.8 ± 11.1 | 74.0 ± 10.3 | < 0.001 | 0.40 | 0.35 |
| Low | 69.1 ± 10.7 | 72.1 ± 10.2 | |||
| Urine volume (ml) | |||||
| NL | 1562 ± 791 | 1636 ± 632 | 0.02 | 0.80 | 0.89 |
| Low | 1806 ± 699 | 1854 ± 709 | |||
| 24 h Na+ exc (mmol) | |||||
| NL | 176.6 ± 95.2 | 187.0 ± 56.5 | < 0.001 | 0.70 | 0.73 |
| Low | 30.1 ± 20.3 | 31.1 ± 12.4 | |||
| 24 h K+ exc (mmol) | |||||
| NL | 57.3 ± 21.7 | 71.7 ± 28.3 | < 0.001 | 0.31 | 0.18 |
| Low | 90.4 ± 21.0 | 90.4 ± 26.5 | |||
| 24 h Cr exc (mg) | |||||
| NL | 1644.3 ± 346.0 | 1678.0 ± 510.5 | 0.28 | 0.88 | 0.27 |
| Low | 1758.5 ± 386.2 | 1677.0 ± 549.6 | |||
Values are means ± s.d. Cr, creatinine; exc, excretion; Pdiet, statistical significance of dietary sodium intake on indices; Pgenotype, statistical significance of genotype effect on indices; Pinteraction, statistical significance of interaction effect on indices (i.e. genotype-by-diet interaction effect on weight loss).