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. 2006 May 11;574(Pt 2):535–546. doi: 10.1113/jphysiol.2006.108829

Figure 8. Effects of DHEAS on muscimol-induced outward currents.

Figure 8

A, whole-cell patch clamp recording from an inspiratory neuron in a P1 medullary slice preparation bathed in 3 mm[K+]o and TTX (1 μm). The neuron was clamped at −58 mV in voltage-clamp mode, and the outward current caused by bath application of muscimol (Mus) recorded. The muscimol-induced current was depressed by bath application of DHEAS (30 μm) and recovered after 5 min washout of DHEAS. B, population data showing the amplitude of outward current measured in response to muscimol (Mus) and muscimol plus DHEAS. Each data point was from five P1 preparations. # indicates significant difference between groups (P < 0.05). Results are expressed as mean ± standard deviation (s.d.)