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. 2006 Apr 27;574(Pt 1):167–181. doi: 10.1113/jphysiol.2006.108621

Figure 2. Activators of the cGMP/GK pathway inhibit electrical activity in ICC.

Figure 2

A and C, the effects of the GC activator YC-1 (30 μm) on STDs and STICS recorded under current clamp and voltage clamp, respectively. B and D, summary data of the effect of YC-1 on STD and STIC frequency obtained from five and six cells, respectively. E and G, the inhibitory effects of the membrane-permeant analogue of cGMP, 8-Br-cGMP (1 mm) on STDs and STICS recorded under current clamp and voltage clamp, respectively. F and H, summary data of the effect of 8-Br-cGMP on STDs and STICS obtained from four cells recorded under the same conditions as those in E and G, respectively.