Table 3.

Dopamine and 5-HT concentrations and C-tau immunoreactive cells in the striatum of rats treated with 5,7-DHT. Concentrations of DA and 5-HT were determined and number of C-tau positive cells were counted in defined regions of the striatum of rats killed 3 days after i.c.v. administration of vehicle or 5,7-DHT (150 μg/10 μl). Values represent mean ± SEM of 3–6 rats.

Drug	DA	5-HT	Striatal C-tau
	(ng/mg tissue ± SEM)		(cell count ± SEM)
Vehicle	16.5 ± 0.59	0.52 ± 0.12	2.58 ± 0.30
5,7-DHT	14.6 ± 0.84	0.15 ± 0.04**	3.56 ± 2.23

^**P < 0.01 compared to vehicle-treated controls.