Table 2.
Subset-specific retention of lymphocyte subsets is restricted to the recirculating lymphocyte pool1
| Lymphocyte subset | PPD stimulated | Saline control |
|---|---|---|
| CD4 | 41·5* (34·5, 48·5) | 37·1 (34·2, 40·0) |
| CD8 | 18·9 (19·5, 18·2) | 18·9 (19·5, 18·2) |
| γδ | 4·6 (5·8, 3·3) | 4·5 (6·2, 2·8) |
| CD21 | 45·7 (43·0, 48·4) | 42·7 (39·2, 32·0) |
1
PPD or saline was infused into the drainage area of prefemoral lymph nodes, which were removed 19 hr later (during the time of maximum lymph node shut-down as measured in the efferent lymph). Cell suspensions were prepared, and the phenotype of cells in the normal and stimulated lymph node compared. No significant differences were evident between the PPD and the saline injected lymph node
*
average of two experiments. Numbers in parentheses give the measured proportion of each subset in each of the two sheep.