Table 1.
Effects of different pathogenic stimuli on DC maturation
| HLADR | CD86 | CD83 | CD40 | |
|---|---|---|---|---|
| LPS | 9/17 (53%) | 15/18 (83%) | 12/16 (75%) | 13/16 (93%) |
| Escherichia coli | 6/8 (75%) | 9/9 (100%) | 4/8 (50%) | 7/8 (87%) |
| Staphylococcusaureus | 3/6 (50%) | 7/7 (100%) | 4/6 (57%) | 4/6 (67%) |
| Salmonella enterica sv. typhimurium | 9/11 (82%) | 11/12 (92%) | 3/10 (30%) | 10/11 (91%) |
| Mycoplasma hominis | 6/9 (67%) | 8/10 (80%) | 4/9 (44%) | 8/9 (89%) |
| Mycobacterium tuberculosis | 4/7 (57%) | 7/8 (87%) | 5/7 (71%) | 5/7 (71%) |
| Trichomonas vaginalis | 6/14 (43%) | 3/14 (21%) | 5/12 (42%) | 3/14 (21%) |
DCs were cultured with the different stimuli for 48 hr and stained for the markers indicated. Results are expressed as the proportion (and percentage) of experiments where the mean fluorescence intensity (MFI) of the marker was up-regulated by more than 10% as compared with the MFI of the marker on immature DCs.